MicroGlycoDB

microglycodb_gene_00086

Gene Number	Cj1149c
Gene Name	gmhA
UniProt ID	Q9PNE6
NOTES - phase variation etc	Sedoheptulose 7-phosphate isomerase (redundant with Cj1424c)
Sugar/modification added	D-glycero-a/b-D-mannoheptose for LOS/CPS
Reviewed	true
Biosynthesis	LOS biosynthesis
Organism	Campylobacter jejuni

functions

sequence

publications

reaction

Data not found

Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.

        10         20         30         40         50

MINLVEKEWQ EHQKIVQASE ILKGQIAKVG ELLCECLKKG GKILICGNGG

        60         70         80         90        100

SAADAQHFAA ELSGRYKKER KALAGIALTT DTSALSAIGN DYGFEFVFSR

       110        120        130        140        150

QVEALGNEKD VLIGISTSGK SPNVLEALKK AKELNMLCLG LSGKGGGMMN

       160        170        180        190

KLCDHNLVVP SDDTARIQEM HILIIHTLCQ IIDESF

1. The genome sequence of the food-borne pathogen Campylobacter jejuni reveals hypervariable sequences.

PubMed: 10688204

doi:10.1038/35001088

2. Deciphering Campylobacter jejuni cell surface interactions from the genome sequence.

PubMed: 11173031

doi:10.1016/s1369-5274(00)00161-2

3. Novel pathways for biosynthesis of nucleotide-activated glycero-manno-heptose precursors of bacterial glycoproteins and cell surface polysaccharides.

PubMed: 12101286

doi:10.1099/00221287-148-7-1979

4. Evidence for acquisition of the lipooligosaccharide biosynthesis locus in Campylobacter jejuni GB11, a strain isolated from a patient with Guillain-Barre syndrome, by horizontal exchange.

PubMed: 14742567

doi:10.1128/iai.72.2.1162-1165.2004

5. Crystal structures of two putative phosphoheptose isomerases.

PubMed: 16477602