microglycodb_gene_00087
| Gene Number | Cj1150c |
|---|---|
| Gene Name | hldE |
| UniProt ID | Q6TG09 |
| NOTES - phase variation etc | Bifunctional: D-glycero-b-D-mannoheptose 7-phosphate kinase / D-glycero-b-D-mannoheptose 1-phosphate adenylyltransferase |
| Sugar/modification added | D-glycero-D-mannohep-1,7-biphosphate and ADP-Hep transferase |
| Reviewed | true |
| Biosynthesis | LOS biosynthesis |
| Organism | Campylobacter jejuni |
functions
sequence
publications
reaction
Data not found
Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate at the C-1 position to selectively form D-glycero-beta-D-manno-heptose-1,7-bisphosphate.
10 20 30 40 50
MLEFLSQQKP KILIIGDFMV DNYTWCDCSR ISPEAPVLIA KTLKEDKRLG
60 70 80 90 100
GAANVYANLK SLGADVFALG VVGDDESGKF LQENLKGEFL IQKGRKTPFK
110 120 130 140 150
NRIMAHNQQV LRLDEEDISE ILLENELIAL FDEKIKDFKA VVLSDYAKGV
160 170 180 190 200
LTPKVCKAVI EKAKVLNIPV LVDPKGSDFN KYSGATLLTP NKKEALEALK
210 220 230 240 250
FENLEGENLE KGIKKLKEDF SLRYSIITLS EAGIALFDEG LKIAPAKALE
260 270 280 290 300
VYDVTGAGDS VIAVLAFCLA NEIEIFKACE LANEAAAVVV SKIGSVSVSF
310 320 330 340 350
DEIKSFKRVD FEKKIKSKEE LLVLLKQNNK KIVFTNGCFD IVHFGHIKYL
360 370 380 390 400
DKAKRLGDVL IVGLNSDASV KRLKGESRPV NSEFQRACML AAFYFVDFVV
410 420 430 440 450
IFDEDTPLEL ISFLKPDILV KGADYKDKLV VGADIVSRVE LIDFEEGFST
460 470
SKIIEKIKDK K
1. The genome sequence of the food-borne pathogen Campylobacter jejuni reveals hypervariable sequences.
PubMed: 10688204
doi:10.1038/35001088
2. Evidence for acquisition of the lipooligosaccharide biosynthesis locus in Campylobacter jejuni GB11, a strain isolated from a patient with Guillain-Barre syndrome, by horizontal exchange.
PubMed: 14742567
doi:10.1128/iai.72.2.1162-1165.2004