microglycodb_gene_00091
| Gene Number | Cj1294 |
|---|---|
| Gene Name | pseC |
| UniProt ID | Q0P8W3 |
| NOTES - phase variation etc | C4 aminotransferase specific for PseB product |
| Sugar/modification added | |
| Reviewed | true |
| Biosynthesis | Flagellin O-glycan biosynthesis |
| Organism | Campylobacter jejuni |
functions
sequence
publications
reaction
Data not found
Catalyzes the second step in the biosynthesis of pseudaminic acid, a sialic-acid-like sugar that is used to modify flagellin. Uses UDP-2-acetamido-2,6-dideoxy-beta-L-arabino-4-hexulose as substrate producing UDP-4-amino-4,6-dideoxy-beta-L-AltNAc.
10 20 30 40 50
MLTYSHQNID QSDIDTLTKA LKDEILTGGK KVNEFEEALC EYMGVKHACV
60 70 80 90 100
LNSATSALHL AYTALGVQEK IVLTTPLTFA ATANAALMAG AKVEFIDIKN
110 120 130 140 150
DGNIDEKKLE ARLLKESENI GAISVVDFAG NSVEMDEISN LTKKYNIPLI
160 170 180 190 200
DDASHALGAL YKSEKVGKKA DLSIFSFHPV KPITTFEGGA VVSDNEELID
210 220 230 240 250
KIKLLRSHGI VKKRLWDSDM VELGYNYRLS DVACALGINQ LKKLDHNLEK
260 270 280 290 300
REEIANFYDK EFEKNPYFST IKIKDYKKSS RHLYPILLFP EFYCQKEELF
310 320 330 340 350
ESLLHAGIGV QVHYKPTYEF SFYKKLLGEI KLQNADNFYK AELSIPCHQE
360 370 380
MNLKDAKFVK DTLFSILEKV KKGYCG
1. The genome sequence of the food-borne pathogen Campylobacter jejuni reveals hypervariable sequences.
PubMed: 10688204
doi:10.1038/35001088
2. Functional characterization of dehydratase/aminotransferase pairs from Helicobacter and Campylobacter: enzymes distinguishing the pseudaminic acid and bacillosamine biosynthetic pathways.
PubMed: 16286454
doi:10.1074/jbc.m511021200
3. Cj1121c, a novel UDP-4-keto-6-deoxy-GlcNAc C-4 aminotransferase essential for protein glycosylation and virulence in Campylobacter jejuni.
PubMed: 16690622
doi:10.1074/jbc.m511714200