microglycodb_gene_00109
| Gene Number | Cj1312 |
|---|---|
| Gene Name | pseG |
| UniProt ID | Q0P8U5 |
| NOTES - phase variation etc | Nucleotidase specific for PseC product, UDP-4-amino4,6-dideoxy-beta-L-AltNAc |
| Sugar/modification added | |
| Reviewed | true |
| Biosynthesis | Flagellin O-glycan biosynthesis |
| Organism | Campylobacter jejuni |
functions
sequence
publications
reaction
Data not found
Nucleotide sugar hydrolase that catalyzes the fourth step in the biosynthesis of pseudaminic acid, a sialic-acid-like sugar that is used to modify flagellin. Mediates the removal of UDP from C-1 of UDP-2,4-diacetamido-2,4,6-trideoxy-beta-L-altropyranose forming 2,4-diacetamido-2,4,6-trideoxy-beta-L-altropyranose.
10 20 30 40 50
MKVLFRSDSS SQIGFGHIKR DLVLAKQYSD VSFACLPLEG SLIDEIPYPV
60 70 80 90 100
YELSSESIYE LINLIKEEKF ELLIIDHYGI SVDDEKLIKL ETGVKILSFD
110 120 130 140 150
DEIKPHHCDI LLNVNAYAKA SDYEGLVPFK CEVRCGFSYA LIREEFYQEA
160 170 180 190 200
KENREKKYDF FICMGGTDIK NLSLQIASEL PKTKIISIAT SSSNPNLKKL
210 220 230 240 250
QKFAKLHNNI RLFIDHENIA KLMNESNKLI ISASSLVNEA LLLKANFKAI
260 270 280
CYVKNQESTA TWLAKKGYEV EYKY
1. The genome sequence of the food-borne pathogen Campylobacter jejuni reveals hypervariable sequences.
PubMed: 10688204
doi:10.1038/35001088
2. PseG of pseudaminic acid biosynthesis: a UDP-sugar hydrolase as a masked glycosyltransferase.
PubMed: 16728396
doi:10.1074/jbc.m602972200
3. Structural and functional analysis of Campylobacter jejuni PseG: a udp-sugar hydrolase from the pseudaminic acid biosynthetic pathway.
PubMed: 19483088
doi:10.1074/jbc.m109.012351