microglycodb_gene_00114

Gene Number Cj1317
Gene Name pseI    
UniProt ID Q0P8U0
NOTES - phase variation etc Pse synthetase
Sugar/modification added
Reviewed true
Biosynthesis Flagellin O-glycan biosynthesis
Organism Campylobacter jejuni
functions
sequence
publications
reaction
Data not found

 Catalyzes the fifth step in the biosynthesis of pseudaminic acid, a sialic-acid-like sugar that is used to modify flagellin. Catalyzes the condensation of phosphoenolpyruvate with 2,4-diacetamido-2,4,6-trideoxy-beta-l-altropyranose, forming pseudaminic acid.

        10         20         30         40         50

MQIGNFNTDK KVFIIAELSA NHAGSLEMAL KSIKAAKKAG ADAIKIQTYT 

        60         70         80         90        100

PDSLTLNSDK EDFIIKGGLW DKRKLYELYE SAKTPYEWHS QIFETAQNEG 

       110        120        130        140        150

ILCFSSPFAK EDVEFLKRFD PIAYKIASFE ANDENFVRLI AKEKKPTIVS 

       160        170        180        190        200

TGIATEEELF KICEIFKEEK NPDLVFLKCT STYPTAIEDM NLKGIVSLKE 

       210        220        230        240        250

KFNVEVGLSD HSFGFLAPVM AVALGARVIE KHFMLDKSIE SEDSKFSLDF 

       260        270        280        290        300

DEFKAMVDAV RQAESALGDG KLDLDEKVLK NRVFARSLYA SKDIKKGEMF 

       310        320        330        340        350

SEENVKSVRP SFGLHPKFYQ ELLGKKASKD IKFGDALKQG DFQ




1. The genome sequence of the food-borne pathogen Campylobacter jejuni reveals hypervariable sequences.

PubMed: 10688204

doi:10.1038/35001088


2. Identification and characterization of NeuB3 from Campylobacter jejuni as a pseudaminic acid synthase.

PubMed: 16120604

doi:10.1074/jbc.m507483200