MicroGlycoDB

microglycodb_gene_00142

Gene Number	Cj1123c
Gene Name	pglD
UniProt ID	Q0P9D1
NOTES - phase variation etc	UDP-N-acetylbacillosamine N-acetyltransferase
Sugar/modification added	diNAcBac biosynthesis
Reviewed	true
Biosynthesis	N-glycan biosynthesis
Organism	Campylobacter jejuni

functions

sequence

publications

reaction

Data not found

Acetyltransferase that modifies the UDP-4-amino-sugar to form UDP-N,N'-diacetylbacillosamine in the N-linked protein glycosylation pathway.

        10         20         30         40         50

MARTEKIYIY GASGHGLVCE DVAKNMGYKE CIFLDDFKGM KFESTLPKYD

        60         70         80         90        100

FFIAIGNNEI RKKIYQKISE NGFKIVNLIH KSALISPSAI VEENAGILIM

       110        120        130        140        150

PYVVINAKAK IEKGVILNTS SVIEHECVIG EFSHVSVGAK CAGNVKIGKN

       160        170        180        190        200

CFLGINSCVL PNLSLADDSI LGGGATLVKN QDEKGVFVGV PAKRM

1. The genome sequence of the food-borne pathogen Campylobacter jejuni reveals hypervariable sequences.

PubMed: 10688204

doi:10.1038/35001088

2. In vitro biosynthesis of UDP-N,N'-diacetylbacillosamine by enzymes of the Campylobacter jejuni general protein glycosylation system.

PubMed: 17087520

doi:10.1021/bi061456h

3. Structure and active site residues of PglD, an N-acetyltransferase from the bacillosamine synthetic pathway required for N-glycan synthesis in Campylobacter jejuni.

PubMed: 18198901

doi:10.1021/bi702032r

4. Crystal structure and catalytic mechanism of PglD from Campylobacter jejuni.

PubMed: 18667421

doi:10.1074/jbc.m801207200

5. Cj1123c (PglD), a multifaceted acetyltransferase from Campylobacter jejuni.

PubMed: 19448740