microglycodb_gene_00144
| Gene Number | Cj1125c |
|---|---|
| Gene Name | pglA |
| UniProt ID | Q0P9C9 |
| NOTES - phase variation etc | Alpha-1,3-N-acetylgalactosaminyltransferase |
| Sugar/modification added | Alpha-1,3 GalNAc |
| Reviewed | true |
| Biosynthesis | N-glycan biosynthesis |
| Organism | Campylobacter jejuni |
functions
sequence
publications
reaction
Data not found
Adds the first GalNAc residue on to the isoprenoid-linked bacillosamine (2,4-diacetamido-2,4,6-trideoxyglucose) carrier in the N-linked protein glycosylation pathway. Acts first on the undecaprenylpyrophosphate-linked bacillosamine (Und-PP-Bac) substrate to yield the disaccharide.
10 20 30 40 50
MRIGFLSHAG ASIYHFRMPI IKALKDRKDE VFVIVPQDEY TQKLRDLGLK
60 70 80 90 100
VIVYEFSRAS LNPFVVLKNF FYLAKVLKNL NLDFIQSAAH KSNTFGILAA
110 120 130 140 150
KWAKIPYRFA LVEGLGSFYI DQGFKANLVR FVINSLYKLS FKFAHQFIFV
160 170 180 190 200
NESNAEFMRN LGLKENKICV IKSVGINLKK FFPIYVESEK KELFWKNLNI
210 220 230 240 250
DKKPIVLMIA RALWHKGVKE FYESATMLKD KANFVLVGGR DENPSCASLE
260 270 280 290 300
FLNSGAVHYL GARSDIVELL QNCDIFVLPS YKEGFPVSVL EAKACGKAIV
310 320 330 340 350
VSDCEGCVEA ISNAYDGLWA KTKNAKDLSE KISLLLEDEK LRLNLAKNAA
360 370 380
QDALQYDENI IAQRYLKLYD RVIKNV
1. The genome sequence of the food-borne pathogen Campylobacter jejuni reveals hypervariable sequences.
PubMed: 10688204
doi:10.1038/35001088
2. In vitro assembly of the undecaprenylpyrophosphate-linked heptasaccharide for prokaryotic N-linked glycosylation.
PubMed: 16186480
doi:10.1073/pnas.0507311102