MicroGlycoDB

microglycodb_gene_00155

Gene Number	Cj1417c
Gene Name
UniProt ID	Q0P8J7
NOTES - phase variation etc	γ-glutamyl-CDP-amidate hydrolase
Sugar/modification added	Nucleotide-activated phosphoramidate biosynthesis
Reviewed	true
Biosynthesis	Capsular polysaccharide biosynthesis
Organism	Campylobacter jejuni

functions

sequence

publications

reaction

Data not found

Involved in the biosynthesis of the O-methyl phosphoramidate (MeOPN) group found on the capsular polysaccharide (CPS) of C.jejuni (PubMed:17675288). Catalyzes the hydrolysis of CDP-L-glutamine to L-glutamate and cytidine diphosphoramidate (PubMed:29023101).

        10         20         30         40         50

MFIGITQRLI CNDSYHEKRE CLALDWGKLF NKDLFKNFTP LPLSYEIDFS

        60         70         80         90        100

YYKHLIKAVI LSGGNDLSFY SPNVLSKKRD LYEKQVIEIC LEEKIPLLGI

       110        120        130        140        150

CRGAQMIAHY FNSHISPCEN HIGKHEVFFS KEKFISNSFH NFAIEKLGED

       160        170        180        190        200

LVELCLAKDN TIEAFKHKYE NIFGIMWHIE RENGLNNIQI LKEWFSLIKE

1. The genome sequence of the food-borne pathogen Campylobacter jejuni reveals hypervariable sequences.

PubMed: 10688204

doi:10.1038/35001088

2. Commonality and biosynthesis of the O-methyl phosphoramidate capsule modification in Campylobacter jejuni.

PubMed: 17675288

doi:10.1074/jbc.m704413200

3. Biosynthesis of nucleoside diphosphoramidates in Campylobacter jejuni.

PubMed: 29023101