MicroGlycoDB

microglycodb_gene_00353

Gene Number	MT1800
Gene Name	pimC
UniProt ID	P0CF99
Protein Name
Reviewed	true
Biosynthesis	PIMs
Organism	Mycobacterium tuberculosis

functions

sequence

publications

reaction

Data not found

Catalyzes the addition of a mannose residue from GDP-D-mannose to the position 6 of the alpha-1,6-linked mannose residue of the triacyl phosphatidylinositol dimannoside (Ac3PIM2) to generate triacyl phosphatidylinositol trimannoside (Ac3PIM3).

        10         20         30         40         50

MRVVQVANFY GPRSGGLRTA VDRLGAEYCA SGHEVFLIVP GARTERHLLR

        60         70         80         90        100

TGVVRITLPA KHIPYTGGYR AVMPGAVRTV LETLRPDALE VSDRLTLRSL

       110        120        130        140        150

GRWGREHGVT TVMISHERLD RFAGQLLPRR AAQKFADFAN ARTAANYDTV

       160        170        180        190        200

VCTTGFAREE FDRIGATNTV TVPLGVDLKT FHPRRRCARV RQHWATPTQI

       210        220        230        240        250

LLVHCGRLSV EKHADRSIDA LAALCDAGVD ARLVIAGEGP LRARLERKAT

       260        270        280        290        300

GLPIDFTGFI SDRHAVAGLL ASADVALAPG PHETFGLAAL ESLACGTPAV

       310        320        330        340        350

VSRTSALTEI ITADSGACAD NRPEAIAHAV RTIVSRPERH RRRCARRRAE

       360        370        380        390

IFTWQRAAAS MLATLGAMAV STRCGDTQDT A

1. Genomic analysis reveals variation between Mycobacterium tuberculosis H37Rv and the attenuated M. tuberculosis H37Ra.

PubMed: 10531227

doi:10.1128/iai.67.11.5768-5774.1999

2. Characterization of a putative alpha-mannosyltransferase involved in phosphatidylinositol trimannoside biosynthesis in Mycobacterium tuberculosis.

PubMed: 11964144

doi:10.1042/0264-6021:3630437

3. Whole-genome comparison of Mycobacterium tuberculosis clinical and laboratory strains.

PubMed: 12218036

doi:10.1128/JB.184.19.5479-5490.2002

4. Whole-genome comparison of Mycobacterium tuberculosis clinical and laboratory strains.