microglycodb_gene_00357
| Gene Number | Rv2174 |
|---|---|
| Gene Name | mptA |
| UniProt ID | O53508 |
| Protein Name | |
| Reviewed | true |
| Biosynthesis | LM |
| Organism | Mycobacterium tuberculosis |
functions
sequence
publications
reaction
Data not found
Involved in the latter stages of the biosynthesis of the alpha-(1->6) mannan core of lipomannan (LM). Catalyzes the addition of alpha-(1->6)-mannose residue.
10 20 30 40 50
MTTPSHAPAV DLATAKDAVV QHLSRLFEFT TGPQGGPARL GFAGAVLITA
60 70 80 90 100
GGLGAGSVRQ HDPLLESIHM SWLRFGHGLV LSSILLWTGV GVMLLAWLGL
110 120 130 140 150
GRRVLAGEAT EFTMRATTVI WLAPLLLSVP VFSRDTYSYL AQGALLRDGL
160 170 180 190 200
DPYAVGPVGN PNALLDDVSP IWTITTAPYG PAFILVAKFV TVIVGNNVVA
210 220 230 240 250
GTMLLRLCML PGLALLVWAT PRLASHLGTH GPTALWICVL NPLVLIHLMG
260 270 280 290 300
GVHNEMLMVG LMTAGIALTV QGRNVAGIIL ITVAIAVKAT AGIALPFLVW
310 320 330 340 350
VWLRHLRERR GYRPVQAFLA AAAISLLIFV AVFAVLSAVA GVGLGWLTAL
360 370 380 390 400
AGSVKIINWL TVPTGAANVI HALGRGLFTV DFYTLLRITR LIGIVIIAVS
410 420 430 440 450
LPLLWWRFRR DDRAALTGVA WSMLIVVLFV PAALPWYYSW PLAVAAPLAQ
460 470 480 490 500
ARRAIAAIAG LSTWVMVIFK PDGSHGMYSW LHFWIATACA LTAWYVLYRS
510 520
PDRRGVQAAT PVVNTP
1. Identification of an alpha(1-->6) mannopyranosyltransferase (MptA), involved in Corynebacterium glutamicum lipomanann biosynthesis, and identification of its orthologue in Mycobacterium tuberculosis.
PubMed: 17714444
doi:10.1111/j.1365-2958.2007.05884.x
2. Proteogenomic analysis of Mycobacterium tuberculosis by high resolution mass spectrometry.
PubMed: 21969609
doi:10.1074/mcp.M111.011445
3. Proteogenomic analysis of Mycobacterium tuberculosis by high resolution mass spectrometry.
PubMed: 21969609
doi:10.1074/mcp.m111.011627
4. Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.
PubMed: 9634230
doi:10.1038/31159