MicroGlycoDB

microglycodb_gene_00369

Gene Number	Rv2962c
Gene Name	ND
UniProt ID	P9WN09
Protein Name
Reviewed	true
Biosynthesis	PGL
Organism	Mycobacterium tuberculosis

functions

sequence

publications

reaction

Data not found

Catalyzes the transfer of the first rhamnosyl residue on p-hydroxybenzoic acid or phenolphthiocerol derivatives to form, after O-methylation at position 2 of the sugar unit, mono-O-methyl-glycosyl-p-hydroxybenzoic acid derivative (p-HBAD I) and 2-O-methyl-rhamnosyl-phenolphthiocerol dimycocerosate (also called mycoside B) during p-hydroxybenzoic acid derivatives (p-HBAD) and glycosylated phenolphthiocerol dimycocerosates (PGL) biosynthesis.

        10         20         30         40         50

MRVSCVYATA SRWGGPPVAS EVRGDAAIST TPDAAPGLAA RRRRILFVAE

        60         70         80         90        100

AVTLAHVVRP FALAQSLDPS RYEVHFACDP RYNQLLGPLP FRHHAIHTIP

       110        120        130        140        150

SERFFGNLTQ GRFYAMRTLR KYVEADLRVL DEIAPDLVVG DLRISLSVSA

       160        170        180        190        200

RLAGIPYIAI ANAYWSPYAQ RRFPLPDVIW TRLFGVRLVK LLYRLERPLL

       210        220        230        240        250

FALQCMPLNW VRRRHGLSSL GWNLCRIFTD GDHTLYADVP ELMPTYDLPA

       260        270        280        290        300

NHEYLGPVLW SPAGKPPTWW DSLPTDRPIV YATLGTSGGR NLLQLVLNAL

       310        320        330        340        350

AELPVTVIAA TAGRSDLKTV PANAFVADYL PGEAAAARSA VVVCNGGSLT

       360        370        380        390        400

TQQALVAGVP VIGVAGNLDQ HLNMEAVERA GAGVLLRTER LKSQRVAGAV

       410        420        430        440        450

MQVISRSEYR QAAARLADAF GRDRVGFPQH VENALRLMPE NRPRTWLAS

1. Characterization of three glycosyltransferases involved in the biosynthesis of the phenolic glycolipid antigens from the Mycobacterium tuberculosis complex.

PubMed: 15292272

doi:10.1074/jbc.m406246200

2. targetTB: a target identification pipeline for Mycobacterium tuberculosis through an interactome, reactome and genome-scale structural analysis.

PubMed: 19099550

doi:10.1186/1752-0509-2-109

3. Proteogenomic analysis of Mycobacterium tuberculosis by high resolution mass spectrometry.

PubMed: 21969609

doi:10.1074/mcp.M111.011445

4. Proteogenomic analysis of Mycobacterium tuberculosis by high resolution mass spectrometry.

PubMed: 21969609

doi:10.1074/mcp.m111.011627

5. Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.

PubMed: 9634230